RNA Details
Disease Name
heart failure
Tissue
heart
RNA Symbol
mir-133a-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
PCR; immunofluorescence etc.
Target
NA
Pathway
PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-133a improves the cardiac function and fibrosis through inhibiting Akt in heart failure rats
Year
2015
Function
miR-133a increased the expression of phosphorylated akt in the heart of chronic heart failure rats.miR-133a mimic and miR-133a overexpression caused a decrease in the heart weight/body weight (hw/bw).